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Monday 23 March 

​13:00                         REGISTRATION (Lunch is not provided on day 1)

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​13:45                         OPENING REMARKS

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​14:00                         SESSION 1: PHAGOCYTOSIS & EFFEROCYTOSIS

 
14:00                         Invited talk

  • β2 integrins impose a mechanical checkpoint on macrophage phagocytosis - Prof. Morgan Huse, USA 

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14:30                         Selected talk

  • Chemical biology reveals the direct redeployment of functional target cell surface proteins to macrophages – Balyn Zaro, USA

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14:45                         Selected talk 

  • Perforin-2: one effector, multiple functions? – Patrycj Kozik, UK

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15:00                        Selected talk 

  • Selective elimination shapes cell composition during gut development – Julia Batki, Germany 

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15:15                         REFRESHMENT BREAK

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16:15                         SESSION 1 cont: PHAGOCYTOSIS & EFFEROCYTOSIS 

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16:15                         Invited talk

  • The regulation of phagosome maturation by phosphoinositides - Prof. Jason King, UK

 

16:45                         Selected talk

  • Mitochondria controls the development of heart resident macrophages, which protect during anthracycline-induced cardiotoxicity through insulin growth factor 1 – Elena Moya-Ruiz, Spain

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17:00                         FLASH TALKS

  • The EGFR/ErbB-tyrosine kinase inhibitor, neratinib, has anti-inflammatory effects by increasing macrophage efferocytosis via the upregulation of MerTK – Kieran Bowden, UK

  • Understanding the pro-reparative functions of neutrophils in bone fracture repair – Jeremie Zappia, UK

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 17:15 – 18:15           The EMBO Keynote Lecture

                                 Prof. Ana-Maria Lennon-Duménil, France 

 

​​​18:30 – 20:30             WELCOME DRINKS RECEPTION

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​​​​Tuesday 24 March 

                        

09:00                          OPENING REMARKS    

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       SESSION 2: PAEDIATRIC INNATE IMMUNITY

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09:15                          Invited talk - Prof. Elisa Gomez Perdiguero, France

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09:45                          Selected talk 

  • Neonatal choroid plexus mast cell activation induces cognitive impairment through serotonergic signaling – Samir Ali-Moussa, France

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10:00                          Selected talk 

  • M-CSF drives alveolar macrophage plasticity during development and infection – Alina Nelipovich, Germany

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10:15                           Selected talk

  • Neutrophils act as a survival niche and driver of Listeria monocytogenes infection in the placenta and fetus – Nikita Raj, Germany

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​10:30                           REFRESHMENTS & POSTER SESSION 1

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​​                                   SESSION 2 cont: PAEDIATRIC INNATE IMMUNITY

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11:30                           Invited talk

  • The role of embryonic macrophages at the maternal-fetal interface - Prof. Melanie Greter, Switzerland 

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12:00                           Selected talk

  • Gut-derived LPS activates hepatic phagocytes prior to gut closure – Julian Brück, Germany

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 ​12:15                          FLASH TALKS

  • Molecular mediators of monocyte cell death driven by inflammatory and metabolic stress – Victor Boyartchuk, Norway

  • Neutrophils impact Th1/Th17 responses during the acute response of Ischaemia-Reperfusion Injury - Julia Jeanette Dielesen, UK

  • Tryptophan depletion generates hyperreactive portal neutrophils in alcoholic liver disease – Mathis Richter, Germany

  • In vivo deuterium labeling of neutrophil precursors in human bone marrow identifies a linear conveyor belt structure of neutrophil development and a mature neutrophil lifespan of 6 days – Nienke Vrisekoop, Netherlands

  • Cardiac-immune microniches program macrophage states in the regenerating heart – Ehsan Razaghi, UK

 

​​12:45                           LUNCH BREAK 

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​                                   SESSION 3: PHAGOCYTE MECHANOSENSING


13:45                           Invited talk 

  • Metabolic redox signalling by the oxoeicosanoid pathway integrates innate immune defence and stress resilience at mucosal linings - Prof. Philipp Niethammer, USA  

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14:15                           Selected talk

  • Role of mechanosensitive Piezo1 channels in phagocytosis by neutrophils – Nicolas Rosa, Switzerland

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14:30                           Selected talk

  • Dissecting two distinct modes of trogocytosis employed by macrophages against cancer cells – Junsang Doh, Republic of Korea

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14:45                           Selected talk

  • Mind the gap: 3D analysis of neutrophil nuclear morphology and function in a single cell – Julia Salafranca, UK

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15:00                           FLASH TALKS

  • Src family kinases Hck, Fgr, and Lyn drive disease progression in experimental immune complex–mediated glomerulonephritis – Dorottya Deli, Hungary

  • Integrin activation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer – Gemma Cairns, UK

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15:15                           REFRESHMENTS & POSTER SESSION 2

 

                                   SESSION 4: PHAGOCYTE FLAVOURS

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16:15                           Invited talk

  • Megakaryocyte emperipolesis arms neutrophils for immune function - Prof. Peter Nigrovic, USA  

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16:45                          Selected talk

  • Neutrophil-derived Ki-67 functions as a molecular brake on PAD4-driven NETosis – Sangeetha Shankar, Germany

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17:00                          Selected talk

  • Multimodal Imaging Reveals Rapid Catecholamine Handling in Human Neutrophils - Linking Inflammation and Coagulation - Luise Erpenbeck, Germany

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17:15                          Selected talk

  • Kupffer cells require cell-intrinsic and systemically aligned circadian clocks to maintain cellular function and liver homeostasis – Siyu Chen, UK

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17:30                          Selected talk

  • Proangiogenic neutrophils fluctuate in numbers in both spleen and endometrium across the estrous cycles – Olha Pavliuk,Sweden

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17:45                         Invited talk

  • Eosinophil heterogeneity in health and disease - Prof. Isabelle Arnold, Switzerland  

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18:15                         FLASH TALKS

  • Dominant perturbation of paraspeckle dynamics and inflammatory responses in macrophages with altered processing of the lncRNA Neat1_2 – Paul Kaufman, USA

  • Probing Neutrophil-Bacteria Interactions and the Behaviour of Engulfed Particles with Optical Tweezers Microrheology During Phagocytosis – Siwenyue Zhang, UK

  • Erythroblast-derived signals imprint neutrophil development – Jesmond Dalli, UK

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18:35                         POSTER CHANGEOVER AND FREE TIME

 

19:30 – 22:00             CONFERENCE DINNER

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Wednesday 25 March 

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      SESSION 5: EVOLUTION & DEVELOPMENT OF PHAGOCYTES  

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08:45                         Invited talk

  • The synovial lining layer develops in the first weeks of life - Prof. Rebecca Gentek, UK  

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09:15                          Selected talk

  • Jagunal homolog 1 safeguards neutrophil immune function by preserving surface sialylation during differentiation – Katrin Nußbaumer, Germany

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09:30                          Selected talk

  • Cataloging salamander phagocytosing immune cell diversity through image-guided sorting and orthogonal transcriptomic approaches – Marlene Oesterle, Sweden

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09:45                           Selected talk  

  • Sex-specific programming of Drosophila phagocytes drives dimorphic outcomes in Staphylococcus aureus infection – Jennifer Regan, UK

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10:00                            Invited talk - Prof. Helen Weavers, UK 

 

​​​10:30                            REFRESHMENTS & POSTER SESSION 3

 

​                                     SESSION 6: PHAGOCYTES IN INFECTION

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11:30                             Invited talk

  • Use of the cytoskeleton to control bacterial infection, Prof. Serge Mostowy, UK  

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12:00                             Selected talk

  • SCAMP3 is necessary for proper granule formation and function in neutrophils – Almke Bader, Germany

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12:15                             Selected talk

  • Combating Sepsis: Investigating the Role of IRF8 and CD163+ Macrophages – Till Jordan, Germany

 

12:30                            Selected talk

  • Type I interferon responses contribute to immune protection against mycobacterial infection - Gillian Tomlinson, UK

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12:45                  ​          LUNCH BREAK 

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                                    SESSION 6: PHAGOCYTES IN INFECTION cont.

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13:45                            Invited talk

  • Tick-tack-tock: neutrophil-circadian immunity in lung cancer - Prof. María Casanova Acebes, Spain

 

14:15                             Selected talk

  • Bone marrow neutrophil reprogramming contributes to NET-associated blood–brain barrier injury in pediatric cerebral malaria – Charalampos Attipa, UK

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14:30                            Selected talk 

  • Synchronized NETs release from neutrophil swarms against Candida albicans – Kirandeep Gill, USA

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14:45                            Selected talk 

  • Investigating the roles of neutrophil dissemination in trained immunity – Elijah Cui, UK

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​​15:00                            FLASH TALKS

  • Programmed neutrophils exhibit enhanced ability to contain secondary infections - Salik Miskat Borbora, UK

  • Mapping neutrophil migration induced by formyl peptides using novel biosensors – Attila Puskás, Hungary

 

​​​​​​​15:15                          REFRESHMENTS & POSTER SESSION 4

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​​                                  SESSION 7: PHAGOCYTE-STROMAL INTERACTIONS IN DISEASES

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16:15                          Invited talk

  • Perivascular Macrophage Populations in the Brain – Inter-relationship with Vascular Basement Membranes - Prof. Lydia Sorokin, Germany

 

16:45                           Selected talk

  • Emerging preneoplastic cells drive pro-tumour neutrophil development through NFkB pathway - Yi Feng, UK

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17:00                           Selected talk

  • A macrophage-derived lipid mediator circuit governs intestinal resilience and sex biased susceptibility to colitis – Emmanuel Albuquerque-Souza, UK

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17:15                           Selected talk

  • Next-generation Green and Red LTB4 Biosensors for Intravital Microscopy – Boldizsár Vámosi, Hungary

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17:30                           Invited talk

  • Unravelling vascular macrophage heterogeneity - Prof. Claudia Monaco, UK

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18:00                           KEYNOTE LECTURE - Prof. Steffen Massberg, Germany

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19:00                           CLOSING CEREMONY & AWARDS ​

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